Modification in media composition to obtain secretory production of STxB-based vaccines using Escherichia coli
نویسندگان
چکیده
منابع مشابه
Production of glycoprotein vaccines in Escherichia coli
BACKGROUND Conjugate vaccines in which polysaccharide antigens are covalently linked to carrier proteins belong to the most effective and safest vaccines against bacterial pathogens. State-of-the art production of conjugate vaccines using chemical methods is a laborious, multi-step process. In vivo enzymatic coupling using the general glycosylation pathway of Campylobacter jejuni in recombinant...
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ژورنال
عنوان ژورنال: Virologica Sinica
سال: 2013
ISSN: 1674-0769,1995-820X
DOI: 10.1007/s12250-013-3286-9